通过双极电极电位识别局部心肌复极时间。
Identification of local myocardial repolarization time by bipolar electrode potential.
作者信息
Namba Tsunetoyo, Todo Takahiro, Yao Takenori, Ashihara Takashi, Haraguchi Ryo, Nakazawa Kazuo, Ikeda Takanori, Ohe Tohru
机构信息
Department of Medical Technology, Kagawa Prefectural College of Health Sciences, Takamatsu, Japan.
出版信息
J Electrocardiol. 2007 Nov-Dec;40(6 Suppl):S97-102. doi: 10.1016/j.jelectrocard.2007.06.022.
PURPOSE
The aim of this study was to investigate whether bipolar electrode potentials (BEPs) reflect local myocardial repolarization dynamics, using computer simulation.
METHODS
Simulated action potential and BEP mapping of myocardial tissue during fibrillation was performed. The BEP was modified to make all the fluctuations have the same polarity. Then, the modified BEP (mBEP) was transformed to "dynamic relative amplitude" (DRA) designed to make all the fluctuations have the similar amplitude.
RESULTS
The repolarization end point corresponded to the end of the repolarization-related small fluctuation that clearly appeared in the DRA of mBEP. Using the DRA of mBEP, we could reproduce the repolarization dynamics in the myocardial tissue during fibrillation.
CONCLUSIONS
The BEP may facilitate identifying the repolarization time. Furthermore, BEP mapping has the possibility that it would be available for evaluating repolarization behavior in myocardial tissue even during fibrillation. The accuracy of activation-recovery interval was also reconfirmed.
目的
本研究旨在通过计算机模拟，探究双极电极电位（BEP）是否反映局部心肌复极动力学。
方法
进行了颤动期间心肌组织的模拟动作电位和BEP映射。对BEP进行修改，使所有波动具有相同极性。然后，将修改后的BEP（mBEP）转换为“动态相对振幅”（DRA），旨在使所有波动具有相似的振幅。
结果
复极终点对应于在mBEP的DRA中清晰出现的与复极相关的小波动的结束。使用mBEP的DRA，我们可以重现颤动期间心肌组织中的复极动力学。
结论
BEP可能有助于识别复极时间。此外，BEP映射有可能可用于评估心肌组织中的复极行为，即使在颤动期间也是如此。还再次证实了激活-恢复间期的准确性。
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