原核生物直系同源基因启动子中保守基序的发现。
Discovery of conserved motifs in promoters of orthologous genes in prokaryotes.
作者信息
Janky Rekin's, van Helden Jacques
机构信息
Université Libre de Bruxelles.
出版信息
Methods Mol Biol. 2007;395:293-308. doi: 10.1007/978-1-59745-514-5_18.
PMID:17993681
Abstract
We present a method to predict cis-acting elements for a given gene by detecting over-represented motifs in promoters of a set of ortholo gous genes in prokaryotes (single-gene, multiple-genomes approach). The method has been used successfully to detect regulatory elements at various taxonomical levels in prokaryotes. A web interface is available at the Regulatory Sequence Analysis Tools site (http://rsat.scmbb.ulb.ac.be/rsat/).
摘要
我们提出了一种通过检测原核生物中一组直系同源基因启动子中过度表达的基序来预测给定基因顺式作用元件的方法（单基因、多基因组方法）。该方法已成功用于检测原核生物不同分类水平上的调控元件。可在调控序列分析工具网站（http://rsat.scmbb.ulb.ac.be/rsat/）获得网络界面。
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