Garagiola Umberto, Maiorana Carlo, Ghiglione Valentino, Marzo Giuseppe, Santoro Franco, Szabò Gyorgy
Department of Oral Surgery and Oral Pathology, Dental and Stomatologic Clinic, School of Dentistry, University of Milan, Milan, Italy.
J Craniofac Surg. 2007 Nov;18(6):1296-304. doi: 10.1097/01.scs.0000246497.62065.5a.
Dental and surgical implant treatment for patients affected by ectodermal dysplasia syndrome can be very complicated. The guided bone regeneration (GBR) membrane technique together with bone grafting is used to facilitate the placement of osseointegrated implants in a prosthetically guided position. Two groups with the same bony anatomical features were assessed. The first consisted of 13 ectodermal dysplasia patients in whom 66 implants with bone grafts and membranes were inserted. In the second control group, 120 implants with GBR were placed in 20 patients. The implants were assessed at the second stage of surgery, and at a follow-up after 1, 2, and 3 years of functional loading. There was no statistically significant difference in the osseointegration rate between the two groups. Despite the anatomical defects associated with the decreased occlusal vertical dimension and the reduced edentulous alveolar ridges, both in height and width, osseointegrated implants together with GBR and bone grafts can be used successfully in patients with ectodermal dysplasia syndrome.
对于受外胚层发育不全综合征影响的患者，牙科和外科植入治疗可能非常复杂。引导骨再生（GBR）膜技术与骨移植一起用于促进骨整合植入物在修复引导位置的放置。评估了具有相同骨解剖特征的两组。第一组由13名外胚层发育不全患者组成，其中插入了66枚带有骨移植和膜的植入物。在第二对照组中，20名患者植入了120枚采用GBR的植入物。在手术的第二阶段以及功能负荷1、2和3年后的随访中对植入物进行评估。两组之间的骨整合率没有统计学上的显著差异。尽管存在与咬合垂直距离减小以及无牙牙槽嵴高度和宽度减小相关的解剖缺陷，但骨整合植入物与GBR和骨移植一起仍可成功用于外胚层发育不全综合征患者。
