外用雄激素、合成代谢物质及类固醇的副作用。简要综述。

Side-effects of topical androgenic and anabolic substances and steroids. A short review.

作者信息

Wollina U, Pabst F, Schönlebe J, Abdel-Naser M B, Konrad H, Gruner M, Haroske G, Klemm E, Schreiber G

机构信息

Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Friedrichstrasse 41, 01067 Dresden, Germany.

出版信息

Acta Dermatovenerol Alp Pannonica Adriat. 2007 Sep;16(3):117-22.

PMID:17994172

Abstract

UNLABELLED

There is an increasing interest, including androgenic and anabolic substances (AAS). The uncritical use may be associated with severe adverse effects. We observed five patients with different patterns of adverse reaction to AAS: two females and three males, they were identified when seeking medical help and advice. The following adverse effects from of AAS have been observed: deepening of the voice due to topical use of AAS in an anti-cellulite cream; circumscribed hypertrichosis and late onset acneiform eruptions due to testosterone replacement therapy after ovariectomy; homolateral gynecomastia and infertility, acne and striae distensae in males using injectable AAS.

CONCLUSIONS

ASS can trigger significant adverse effects. An interdisciplinary approach may be necessary for evaluation. The dermatologists should be familiar with the adverse effects.

摘要

未标注

人们对包括雄激素和合成代谢物质（AAS）在内的物质兴趣日益浓厚。不加区分地使用可能会带来严重的不良反应。我们观察了五名对AAS有不同不良反应模式的患者：两名女性和三名男性，他们在寻求医疗帮助和建议时被确诊。已观察到AAS产生的以下不良反应：因在抗橘皮组织霜中局部使用AAS导致声音变低沉；卵巢切除术后因睾酮替代疗法导致局限性多毛症和迟发性痤疮样皮疹；使用注射用AAS的男性出现同侧乳腺增生、不育、痤疮和膨胀纹。