Chernitskiĭ E A, Bolodon V N, Vorobeĭ A V
Biofizika. 1991 Sep-Oct;36(5):855-7.
It is shown that during sensitized by haematoporphyrin photooxidation accumulation of TBA-active products in destroyed cells (human erythrocytes, rat thymocytes, pig leucocytes) occurs considerably faster than in the intact ones. Similar acceleration is observed in intact erythrocytes after the amount of reduced glutathione in it was decreased. It is supposed that the cause of intensification processes of lipid peroxidation consists in separation of the antioxidant system from the plasma membrane.
结果表明，在血卟啉光氧化致敏过程中，受损细胞（人红细胞、大鼠胸腺细胞、猪白细胞）中TBA活性产物的积累比完整细胞快得多。当完整红细胞内还原型谷胱甘肽含量降低后，也观察到类似的加速现象。据推测，脂质过氧化过程加剧的原因在于抗氧化系统与质膜分离。
