Hunt John
Department of Pediatrics (Pulmonology, Allergy and Immunology), Box 800386, University of Virginia, Charlottesville, VA 22908, USA.
Immunol Allergy Clin North Am. 2007 Nov;27(4):587-96; v. doi: 10.1016/j.iac.2007.09.001.
Exhaled breath condensate (EBC) is a promising source of biomarkers of lung disease. EBC is not a biomarker, but rather a matrix in which biomarkers may be identified, in that way equivalent to blood, sweat, tears, urine, and saliva. EBC may be thought of either as a body fluid or as a condensate of exhaled gas. The field of EBC research has advanced gradually, with the debates surrounding an emerging field helping to pose questions and gradually leading to answers. Conscientious assay technique will likely find in EBC any substance of substantially high enough concentration in the airway lining fluid.
呼出气体冷凝液(EBC)是肺部疾病生物标志物的一个有前景的来源。EBC本身并非生物标志物,而是一种可用于识别生物标志物的基质,从这方面来说它与血液、汗液、泪水、尿液和唾液类似。EBC既可以被视为一种体液,也可以被视为呼出气体的冷凝物。EBC研究领域是逐步发展起来的,围绕这个新兴领域的争论有助于提出问题并逐渐得出答案。严谨的检测技术很可能会在EBC中发现气道衬里液中任何浓度足够高的物质。