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呼出气冷凝物:综述。

Exhaled breath condensate: an overview.

作者信息

Hunt John

机构信息

Department of Pediatrics (Pulmonology, Allergy and Immunology), Box 800386, University of Virginia, Charlottesville, VA 22908, USA.

出版信息

Immunol Allergy Clin North Am. 2007 Nov;27(4):587-96; v. doi: 10.1016/j.iac.2007.09.001.

Abstract

Exhaled breath condensate (EBC) is a promising source of biomarkers of lung disease. EBC is not a biomarker, but rather a matrix in which biomarkers may be identified, in that way equivalent to blood, sweat, tears, urine, and saliva. EBC may be thought of either as a body fluid or as a condensate of exhaled gas. The field of EBC research has advanced gradually, with the debates surrounding an emerging field helping to pose questions and gradually leading to answers. Conscientious assay technique will likely find in EBC any substance of substantially high enough concentration in the airway lining fluid.

摘要

呼出气体冷凝液(EBC)是肺部疾病生物标志物的一个有前景的来源。EBC本身并非生物标志物,而是一种可用于识别生物标志物的基质,从这方面来说它与血液、汗液、泪水、尿液和唾液类似。EBC既可以被视为一种体液,也可以被视为呼出气体的冷凝物。EBC研究领域是逐步发展起来的,围绕这个新兴领域的争论有助于提出问题并逐渐得出答案。严谨的检测技术很可能会在EBC中发现气道衬里液中任何浓度足够高的物质。

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2
Exhaled breath condensate pH and childhood asthma: unselected birth cohort study.
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3
Cytokines in exhaled breath condensate of children with asthma and cystic fibrosis.
Ann Allergy Asthma Immunol. 2006 Feb;96(2):349-55. doi: 10.1016/S1081-1206(10)61247-1.
4
Normative data for pH of exhaled breath condensate.
Chest. 2006 Feb;129(2):426-430. doi: 10.1378/chest.129.2.426.
5
Assaying all of the nitrogen oxides in breath modifies the interpretation of exhaled nitric oxide.
Vascul Pharmacol. 2005 Dec;43(6):379-84. doi: 10.1016/j.vph.2005.08.003. Epub 2005 Oct 10.
6
Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease.
Respir Med. 2005 Oct;99(10):1229-40. doi: 10.1016/j.rmed.2005.02.041. Epub 2005 Apr 12.
7
Exhaled breath condensate: methodological recommendations and unresolved questions.
Eur Respir J. 2005 Sep;26(3):523-48. doi: 10.1183/09031936.05.00029705.
8
Epithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects.
J Appl Physiol (1985). 2005 Oct;99(4):1286-92. doi: 10.1152/japplphysiol.00362.2005. Epub 2005 May 26.
9
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10
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Pediatr Pulmonol. 2004 Mar;37(3):273-5. doi: 10.1002/ppul.10431.

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