Anwar M U, Al Ghazal S K, Boome R S
Department of Plastic Surgery, Bradford Teaching Hospital Trust, Bradford, West Yorkshire, United Kingdom.
J Hand Surg Am. 2007 Nov;32(9):1423-8. doi: 10.1016/j.jhsa.2007.06.015.
Dupuytren's disease is not as commonly reported in women as in men. Our literature search yielded only two such studies. The purpose of this study was to further examine the presentation and surgical outcome of Dupuytren's disease in women, including complications and to compare these outcomes to a similar cohort of men and to previous studies of Dupuytren's disease in women.
A retrospective case series review was undertaken, and we identified all women who were admitted for surgical correction of Dupuytren's disease since 1990. Comparison was made with men operated during the same period. Pre- and postoperative measurements for lack of extension at the metacarpophalangeal joint (MCPJ), proximal interphalangeal (PIP) joint, and distal interphalangeal (DIP) joint were made by the senior author. SPSS (Statistical Package for the Social Sciences, SPSS Inc., Chicago, Il) was used for statistical analysis. The t test was used to compare the two groups.
One hundred nine women were identified, with 119 operated hands, out of a total of 657 patients operated. Comparisons were made with 548 men. The average age at presentation was 63 years in women, and there was no significant difference between the two groups. One hundred five of the patients had digital involvement. The little and ring fingers were involved most frequently. Thirty-four had involvement of the MCPJ. Mean preoperative contracture was 35 degrees . Mean postoperative contracture was 1 degrees . Proximal interphalangeal joint involvement was seen in 66 patients. Mean preoperative contracture was 42 degrees . Mean postoperative contracture was 7 degrees . Distal joint involvement was identified in only 4 digits. There was no statistical difference with the men as regards digital involvement and joint involvement; however, correction at the PIP joint was significantly lower. Fasciectomy was performed in 107 cases (90%), fasciectomy and local flap in 7 cases (6%), and dermafasciectomy in 5 cases (4%). The most common complication was digital nerve/artery injury (6 patients), and disease recurrence rate was 22%. These were statistically similar to the men.
Dupuytren's disease is less prevalent in women but its symptomatic presentation is similar to that in men, with more severe involvement of the PIP joint and a similar recurrence rate. The surgical outcomes, however, were equivalent with regard to final contracture correction, recurrence, and complication rates.
杜普伊特伦挛缩症在女性中的报道不如男性常见。我们的文献检索仅发现两项此类研究。本研究的目的是进一步研究女性杜普伊特伦挛缩症的表现和手术结果,包括并发症,并将这些结果与类似的男性队列以及先前关于女性杜普伊特伦挛缩症的研究进行比较。
进行了一项回顾性病例系列研究,我们确定了自1990年以来因杜普伊特伦挛缩症接受手术矫正的所有女性。与同期接受手术的男性进行比较。由资深作者对掌指关节(MCPJ)、近端指间关节(PIP)和远端指间关节(DIP)伸展受限的术前和术后测量值进行记录。使用SPSS(社会科学统计软件包,SPSS公司,伊利诺伊州芝加哥)进行统计分析。采用t检验比较两组。
在总共657例接受手术的患者中,确定了109名女性,她们有119只接受手术的手。与548名男性进行了比较。女性患者就诊时的平均年龄为63岁,两组之间无显著差异。105例患者有手指受累。小指和环指受累最为频繁。34例患者掌指关节受累。术前平均挛缩角度为35度。术后平均挛缩角度为1度。66例患者近端指间关节受累。术前平均挛缩角度为42度。术后平均挛缩角度为7度。仅4个手指发现远端关节受累。在手指受累和关节受累方面与男性无统计学差异;然而,近端指间关节的矫正明显较低。107例(90%)进行了筋膜切除术,7例(6%)进行了筋膜切除术和局部皮瓣手术,5例(4%)进行了皮肤筋膜切除术。最常见的并发症是指神经/动脉损伤(6例患者),疾病复发率为22%。这些在统计学上与男性相似。
杜普伊特伦挛缩症在女性中不太常见,但其症状表现与男性相似,近端指间关节受累更严重,复发率相似。然而,在最终挛缩矫正、复发和并发症发生率方面,手术结果相当。