Marx M V, Tauscher J R, Williams D M, Greenfield L J
Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109.
J Vasc Interv Radiol. 1991 May;2(2):261-8. doi: 10.1016/s1051-0443(91)72292-6.
An animal model was used to evaluate the utility of intravascular ultrasound (US) imaging of the inferior vena cava (IVC) following Greenfield filter placement. Ten Greenfield filters were placed in the IVCs of five sheep and three dogs. Experimentally induced thrombi were injected into four filters at the time of placement. Intravascular US and cavography were performed 4 weeks after filter implant. The imaging studies were evaluated for demonstration of filter position, orientation, and leg distribution, as well as prediction of caval wall penetration by filter hooks. Experimentally induced and spontaneous intrafilter thrombi were also imaged. Findings were compared with those of postmortem examination. Exact filter position and orientation were most simply and accurately demonstrated on radiographs. Filter leg distribution and extent of intrafilter thrombus were best evaluated on intravascular US images. The prevalence of caval wall penetration was underestimated with both studies. The results of this animal study suggest that the information about the IVC provided at cavography and intravascular US following Greenfield filter placement may be complementary.
使用动物模型评估格林菲尔德滤器置入后下腔静脉（IVC）血管内超声（US）成像的效用。在五只绵羊和三只狗的下腔静脉中置入了十个格林菲尔德滤器。在置入时，将实验诱导的血栓注入四个滤器中。滤器植入后4周进行血管内超声检查和腔静脉造影。对成像研究进行评估，以显示滤器位置、方向和腿部分布，以及预测滤器钩对腔静脉壁的穿透情况。还对实验诱导的和自发形成的滤器内血栓进行成像。将结果与尸检结果进行比较。在X线片上最能简单且准确地显示滤器的确切位置和方向。在血管内超声图像上最能评估滤器腿部分布和滤器内血栓范围。两项研究均低估了腔静脉壁穿透的发生率。这项动物研究的结果表明，格林菲尔德滤器置入后腔静脉造影和血管内超声所提供的关于下腔静脉的信息可能具有互补性。
