Gerami Pedram, Guitart Joan
Department of Dermatology, Northwestern University and Medical Center, The Feinberg School of Medicine, Chicago, IL 60611, USA.
J Cutan Pathol. 2007 Dec;34 Suppl 1:29-32. doi: 10.1111/j.1600-0560.2007.00722.x.
Follicular mycosis fungoides is an increasingly recognized subtype of mycosis fungoides. There is great variability in the clinical and histologic presentation of this variant of mycosis fungoides. Epithelial hyperplasia may occur in cutaneous lymphomas, and basaloid induction of the epidermis is a recognized phenomenon in cutaneous neoplasms. We have identified three patients with follicular mycosis fungoides with basaloid folliculolymphoid hyperplasia, a finding that has received little attention in the literature. The patients were all men with prominent follicular papules on the face. We believe that these changes are a distinctive histologic pattern of follicular mycosis fungoides. Hence, we describe the clinical-pathologic findings of basaloid folliculolymphoid hyperplasia in these three patients with follicular mycosis fungoides.
毛囊性蕈样肉芽肿是一种越来越被认可的蕈样肉芽肿亚型。这种蕈样肉芽肿变体的临床和组织学表现存在很大差异。上皮增生可能发生在皮肤淋巴瘤中,表皮的基底样化生是皮肤肿瘤中一种公认的现象。我们发现了3例患有毛囊性蕈样肉芽肿伴基底样毛囊淋巴样增生的患者,这一发现此前在文献中很少受到关注。这些患者均为男性,面部有明显的毛囊丘疹。我们认为这些改变是毛囊性蕈样肉芽肿独特的组织学模式。因此,我们描述了这3例毛囊性蕈样肉芽肿患者基底样毛囊淋巴样增生的临床病理表现。