Dick L, Mauro M A, Jaques P F, Buckingham P
Department of Radiology, University of North Carolina Hospitals, Chapel Hill 27599-7510.
J Vasc Interv Radiol. 1991 Aug;2(3):327-9. doi: 10.1016/s1051-0443(91)72253-7.
Ninety-six patients undergoing radiologically guided placement of 104 Hickman catheters were grouped according to their human immunodeficiency virus (HIV) serologic status. Infectious complications were categorized according to their severity (local or systemic) and time of occurrence (periprocedural or late). The number of infectious complications per 100 indwelling catheter days was calculated. Among the 14 catheter placements in 13 HIV-positive patients, two systemic infections occurred, resulting in a 14% overall infection rate and 0.18 infectious complications per 100 indwelling catheter days. The remaining 83 HIV-negative patients underwent 90 Hickman catheter placements. Nine infectious complications (10%) were noted in the 90 catheters, translating into 0.19 infectious complications per 100 indwelling catheters days. These results suggest no significant (relative risk [RR] of 1.4 and .95) difference in infectious complication rates encountered in HIV-positive patients compared with the general population. This supports the clinical usefulness of Hickman catheter placement in HIV-positive patients, although many additional HIV-positive patients must be evaluated to achieve an acceptable level of statistical confidence.
96例接受104根希克曼导管放射引导置入术的患者,根据其人类免疫缺陷病毒(HIV)血清学状态进行分组。感染并发症根据其严重程度(局部或全身)和发生时间(围手术期或后期)进行分类。计算每100个留置导管日的感染并发症数量。在13例HIV阳性患者的14次导管置入术中,发生了2例全身感染,总体感染率为14%,每100个留置导管日的感染并发症为0.18例。其余83例HIV阴性患者接受了90次希克曼导管置入术。在90根导管中发现9例感染并发症(10%),即每100个留置导管日有0.19例感染并发症。这些结果表明,与普通人群相比,HIV阳性患者的感染并发症发生率没有显著差异(相对风险[RR]为1.4和0.95)。这支持了在HIV阳性患者中置入希克曼导管的临床实用性,尽管必须评估更多的HIV阳性患者以达到可接受的统计置信水平。