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认识阿尔茨海默病中的淡漠症状。

Recognizing apathy in Alzheimer's disease.

作者信息

Lerner Alan J, Strauss Milton, Sami Susie A

机构信息

Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

出版信息

Geriatrics. 2007 Nov;62(11):14-7.

PMID:17999565
Abstract

Apathy has been increasingly recognized as a neuropsychiatric symptom in many neurologic disorders. In this paper, we review the clinical features of apathy in Alzheimer's disease. We also review screening, the differential diagnosis including depression, medical illnesses, and mild cognitive impairment, and treating modalities and issues. It must also be recognized that apathy per se almost never occurs as an isolated syndrome, so it must be viewed in the context of an individual's entire behavioral and cognitive status.

摘要

冷漠已越来越多地被视为许多神经系统疾病中的一种神经精神症状。在本文中,我们回顾了阿尔茨海默病中冷漠的临床特征。我们还回顾了筛查、鉴别诊断(包括抑郁症、躯体疾病和轻度认知障碍)以及治疗方式和相关问题。还必须认识到,冷漠本身几乎从不作为一种孤立的综合征出现,因此必须在个体的整体行为和认知状态背景下看待它。

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J Alzheimers Dis. 2009;16(3):577-83. doi: 10.3233/JAD-2009-0994.
2
Is getting older all that rewarding?变老真的都那么值得吗?
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14751-2. doi: 10.1073/pnas.0807850105. Epub 2008 Sep 23.