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[急性脑血管疾病中的酸碱失衡]

[Acid-base imbalance in acute cerebrovascular diseases].

作者信息

Huang R

机构信息

Sun Yatsen University of Medical Sciences, Guangzhou.

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1991 Dec;24(6):355-7, 384.

PMID:1800063
Abstract

Ninety cases of cerebral hemorrhage or infarction confirmed with CT scans were reported. Blood specimens were taken within 4 to 24 hours after the onset of the strokes for blood gas analysis. The results showed that respiratory alkalosis occurred in all patients with cerebral hemorrhage or embolism, while the metabolic acidosis accompanied only those with severe cerebral infarctions or intracerebral hematomas rupturing into the ventricles small local infarcts caused only hypoxemia or no changes at all. It seemed likely that the blood acid-base changes were closely related to the nature and the size of the lesions. It was suggested that since hyperventilation caused by cerebral lesions might be the main factor that give rise to respiratory alkalosis, it would be of great importance to maintain the acid base balance in the acute stage of the stroke with proper dehydration therapy and oxygen administration.

摘要

报告了90例经CT扫描确诊的脑出血或脑梗死病例。在中风发作后4至24小时内采集血标本进行血气分析。结果显示,所有脑出血或栓塞患者均出现呼吸性碱中毒,而代谢性酸中毒仅见于重度脑梗死或脑内血肿破入脑室的患者,小面积局部梗死仅导致低氧血症或无变化。血液酸碱变化似乎与病变的性质和大小密切相关。提示由于脑部病变引起的过度通气可能是导致呼吸性碱中毒的主要因素,因此在中风急性期通过适当的脱水治疗和给氧来维持酸碱平衡具有重要意义。

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引用本文的文献

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Severe Respiratory Alkalosis in Acute Ischemic Stroke: A Rare Presentation.急性缺血性卒中伴严重呼吸性碱中毒:一种罕见的表现
Cureus. 2020 Apr 20;12(4):e7747. doi: 10.7759/cureus.7747.