Kim Deok Won, Kim Sung Woo, Kim Soo Chan, Nam Ki Chang, Kang Eun Seok, Im Jae Jung
Department of Medical Engineering, College of Medicine, Yonsei University, Seoul, 120-752 Korea.
Annu Int Conf IEEE Eng Med Biol Soc. 2007;2007:2211-4. doi: 10.1109/IEMBS.2007.4352763.
Nerve conduction velocity (NCV) has been used as a standard method for diagnosing diabetic neuropathy. However, strong electric stimulus causes stress and pain. The purpose of this study is to suggest a simple screening method for detecting diabetic neuropathic foot caused from nerve damages in the legs. Photoplethysmography (PPG) and Laser Doppler (LD) were utilized to measure the blood volume changes and perfusions from fingers and toes. As a result of the PPG signal measurements, ratios of toe to finger obtained from the neuropathy group were significantly higher than those of the normal group (p <0.001). Sensitivities of the PPG method were found to be 98.0 % for both sides. Specificities were found to be 98.4 % for the left and 92.2% for the right side. The suggested PPG method is reliable, simple, low-cost, and noninvasive which could become an effective new screening tool for the early detection of diabetic neuropathic foot.
神经传导速度（NCV）一直被用作诊断糖尿病神经病变的标准方法。然而，强电刺激会引起压力和疼痛。本研究的目的是提出一种简单的筛查方法，用于检测由腿部神经损伤引起的糖尿病神经病变足。采用光电容积脉搏波描记法（PPG）和激光多普勒（LD）测量手指和脚趾的血容量变化及灌注情况。通过PPG信号测量结果发现，神经病变组的趾指比显著高于正常组（p<0.001）。PPG方法两侧的敏感性均为98.0%。左侧的特异性为98.4%，右侧为92.2%。所建议的PPG方法可靠、简单、低成本且无创，可成为早期检测糖尿病神经病变足的有效新型筛查工具。
Zotero 插件