Constantoyannis Constantine, Kagadis George, Chroni Elisabeth
University of Patras--Neurosurgery, Rion, Greece.
Headache. 2008 Jan;48(1):130-4. doi: 10.1111/j.1526-4610.2007.00961.x. Epub 2007 Nov 13.
This prospective study aimed to evaluate the results of percutaneous trigeminal ganglion balloon compression (BC) in patients with various types of trigeminal neuralgia (TN) and autonomic cephalalgia.
Twenty-five consecutive patients underwent BC and were followed up for 27-60 months. They were divided into 2 groups: group A (n=18) patients with idiopathic TN and group B (n=7) patients with secondary TN (n=5) and trigeminal autonomic cephalalgia (TAC) (n=2).
Postoperatively, 15 patients in group A experienced pain relief, one required medication and 2 had no response; in group B, 6 were free of pain, including the 2 patients with TAC, and one required medication. Complications in both groups were either functionally trivial or infrequent. None of the patients developed keratitis or anesthesia dolorosa. Pain recurrence occurred early (<6 months) in one patient from group B, and late in 2 patients from group A.
Balloon compression is a minimally invasive procedure that seems to be comparably successful for idiopathic and secondary TN, as well as TAC. However, further studies are deemed necessary to establish it as the first-line treatment in medically resistant trigeminal pain.
本前瞻性研究旨在评估经皮三叉神经节球囊压迫术（BC）治疗各种类型三叉神经痛（TN）和自主神经性头痛的效果。
连续25例患者接受了BC治疗，并随访27至60个月。他们被分为两组：A组（n = 18）为特发性TN患者，B组（n = 7）为继发性TN患者（n = 5）和三叉神经自主性头痛（TAC）患者（n = 2）。
术后，A组15例患者疼痛缓解，1例需要药物治疗，2例无反应；B组6例疼痛消失，包括2例TAC患者，1例需要药物治疗。两组的并发症在功能上均较轻或不常见。所有患者均未发生角膜炎或痛性麻木。B组1例患者疼痛早期复发（<6个月），A组2例患者疼痛晚期复发。
球囊压迫术是一种微创手术，对于特发性和继发性TN以及TAC似乎同样成功。然而，有必要进行进一步研究，以将其确立为难治性三叉神经痛的一线治疗方法。
