Bomblies Kirsten, Weigel Detlef
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076, Tübingen, Germany.
Curr Opin Genet Dev. 2007 Dec;17(6):500-4. doi: 10.1016/j.gde.2007.09.006. Epub 2007 Nov 19.
What genetic and epigenetic changes underlie adaptation and divergence? Arabidopsis thaliana and its relatives are increasingly being employed to address such central questions of evolutionary biology. For example, comparative, genomic and classical genetic approaches are revealing mechanisms underlying processes relevant to speciation, including mating system evolution, the effects of ploidy and other chromosomal differences, and the roles that specific genes might play in Dobzhansky-Muller type incompatibilities. The considerable body of knowledge and resources available for A. thaliana and improvements in tools and technology applied to its close relatives are opening doors for combining experimental and comparative analyses to elucidate fundamental mechanisms of evolution.
适应性和分化背后的遗传和表观遗传变化是什么?拟南芥及其近缘种越来越多地被用于解决进化生物学的此类核心问题。例如,比较基因组学和经典遗传学方法正在揭示与物种形成相关过程的潜在机制,包括交配系统进化、多倍体和其他染色体差异的影响,以及特定基因在多布赞斯基-穆勒型不相容性中可能发挥的作用。拟南芥现有的大量知识和资源,以及应用于其近缘种的工具和技术的改进,为结合实验分析和比较分析以阐明进化的基本机制打开了大门。