Nakagawa Kouichi, Ikota Nobuo, Anzai Kazunori
RI Research Center, Fukushima Medical University, 1 Hikarigaoka, Fukushima 960-1295, Japan.
Spectrochim Acta A Mol Biomol Spectrosc. 2008 May;69(5):1384-7. doi: 10.1016/j.saa.2007.09.041. Epub 2007 Oct 6.
We investigated the sucrose radical-production cross-section induced by heavy-ion irradiation. L-alanine was also used in order to compare radical yield and cross-section. The stable free radicals after irradiation were analyzed by electron paramagnetic resonance (EPR). The radical yield obtained by the irradiated samples had a logarithmic correlation with the LET (linear energy transfer). Quantitative EPR analyses showed that radical productions for sucrose and L-alanine vary both by different particle irradiation and the LET under the same absorbed dose. Furthermore, the cross-sections of radical productions for samples were calculated. Both cross-sections for C ions irradiation under LET 30 keV/microm at 50 Gy dose were approximately 3.0x10(-9) microm(2), taking account of the molecular areas of the samples. The values of the cross-sections imply that multiple ionizing particles involve producing stable radicals.
我们研究了重离子辐照诱导的蔗糖自由基产生截面。还使用了L-丙氨酸以比较自由基产率和截面。通过电子顺磁共振(EPR)分析辐照后的稳定自由基。辐照样品获得的自由基产率与传能线密度(LET)呈对数相关。定量EPR分析表明,蔗糖和L-丙氨酸的自由基产生因不同的粒子辐照以及相同吸收剂量下的LET而有所不同。此外,还计算了样品的自由基产生截面。考虑到样品的分子面积,在50 Gy剂量下LET为30 keV/μm时,碳离子辐照的两个截面约为3.0×10⁻⁹μm²。截面值表明多个电离粒子参与了稳定自由基的产生。