Kane Robert L, Shamliyan Tatyana A, Mueller Christine, Duval Sue, Wilt Timothy J
University of Minnesota School of Public Health, Minneapolis, Minnesota 55455, USA.
Med Care. 2007 Dec;45(12):1195-204. doi: 10.1097/MLR.0b013e3181468ca3.
To examine the association between registered nurse (RN) staffing and patient outcomes in acute care hospitals.
Twenty-eight studies reported adjusted odds ratios of patient outcomes in categories of RN-to-patient ratio, and met inclusion criteria. Information was abstracted using a standardized protocol.
Random effects models assessed heterogeneity and pooled data from individual studies. Increased RN staffing was associated with lower hospital related mortality in intensive care units (ICUs) [odds ratios (OR), 0.91; 95% confidence interval (CI), 0.86-0.96], in surgical (OR, 0.84; 95% CI, 0.80-0.89), and in medical patients (OR, 0.94; 95% CI, 0.94-0.95) per additional full time equivalent per patient day. An increase by 1 RN per patient day was associated with a decreased odds ratio of hospital acquired pneumonia (OR, 0.70; 95% CI, 0.56-0.88), unplanned extubation (OR, 0.49; 95% CI, 0.36-0.67), respiratory failure (OR, 0.40; 95% CI, 0.27-0.59), and cardiac arrest (OR, 0.72; 95% CI, 0.62-0.84) in ICUs, with a lower risk of failure to rescue (OR, 0.84; 95% CI, 0.79-0.90) in surgical patients. Length of stay was shorter by 24% in ICUs (OR, 0.76; 95% CI, 0.62-0.94) and by 31% in surgical patients (OR, 0.69; 95% CI, 0.55-0.86).
Studies with different design show associations between increased RN staffing and lower odds of hospital related mortality and adverse patient events. Patient and hospital characteristics, including hospitals' commitment to quality of medical care, likely contribute to the actual causal pathway.
探讨急症医院注册护士(RN)配备与患者预后之间的关联。
28项研究报告了按RN与患者比例分类的患者预后调整比值比,并符合纳入标准。使用标准化方案提取信息。
随机效应模型评估异质性并汇总来自各个研究的数据。在重症监护病房(ICU),每增加一名全职等效护士(每患者日),RN配备增加与医院相关死亡率降低相关[比值比(OR),0.91;95%置信区间(CI),0.86 - 0.96],在外科患者中(OR,0.84;95%CI,0.80 - 0.89),在内科患者中(OR,0.94;95%CI,0.94 - 0.95)。在ICU中,每患者日增加1名RN与医院获得性肺炎的比值比降低相关(OR,0.70;95%CI,0.56 - 0.88)、意外拔管(OR,0.49;95%CI,0.36 - 0.67)、呼吸衰竭(OR,0.40;95%CI,0.27 - 0.59)和心脏骤停(OR,0.72;95%CI,0.62 - 0.84),在外科患者中抢救失败风险较低(OR,0.84;95%CI,0.79 - 0.90)。在ICU住院时间缩短24%(OR,0.76;95%CI,0.62 - 0.94),在外科患者中缩短31%(OR,0.69;95%CI,0.55 - 0.86)。
不同设计的研究表明,增加RN配备与降低医院相关死亡率和不良患者事件的几率之间存在关联。患者和医院特征,包括医院对医疗质量的承诺,可能促成了实际的因果途径。