Yoshimizu T, Suga K, Orihashi N, Soejima K, Kaneko T, Kawamura M, Nakanishi T, Utsumi H, Yamada N
Department of Radiology, Yamaguchi University School of Medicine.
Kaku Igaku. 1991 Oct;28(10):1151-7.
The lesions of sarcoidosis generally show relatively high Ga-67 uptake and the usefulness of scintigraphy using this agent in the evaluation of lesion activity is well known. In this report, we assessed characteristic uptake of Ga-67 in intrathoracic lymphnodes, the shape of which resembled the Greek letter Lambda (Lambda sign) and a symmetrical accumulation in bilateral lacrimal and salivary glands which resembled a Panda face (Panda sign) in patients with sarcoidosis. Our review of Ga-67 scans obtained from 15 patients with sarcoidosis and 1,779 patients with other disorders during the past 3 years revealed that the simultaneous presence of both Lambda and Panda signs was specific to patients with sarcoidosis and was not found in patients with various other disorders, although one of these signs might be observed in patients without sarcoidosis. When Lambda-like sign was observed, chest radiogram or CT was necessary for the differential diagnosis of sarcoidosis. Panda sign was observed frequently among patients who had previously received irradiation of the neck. Our results confirmed that sarcoidosis must be suspected when both Lambda and Panda signs were observed.
结节病的病变通常显示镓-67摄取相对较高，并且使用该剂进行闪烁显像在评估病变活动中的作用是众所周知的。在本报告中，我们评估了结节病患者胸内淋巴结中镓-67的特征性摄取，其形状类似希腊字母λ（λ征），以及双侧泪腺和唾液腺中的对称性积聚，类似熊猫脸（熊猫征）。我们回顾了过去3年中从15例结节病患者和1779例其他疾病患者获得的镓-67扫描结果，发现λ征和熊猫征同时出现是结节病患者特有的，在其他各种疾病患者中未发现，尽管在无结节病的患者中可能观察到其中一个征象。当观察到类似λ征时，胸部X线片或CT对于结节病的鉴别诊断是必要的。熊猫征在先前接受过颈部照射的患者中经常观察到。我们的结果证实，当同时观察到λ征和熊猫征时，必须怀疑结节病。
