Aydíner A, Aras T, Oto A, Oram E, Gedik O, Bekdik C F, Oram A, Uğurlu S, Karamehmetoğlu A
Department of Cardiology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
Nuklearmedizin. 1991 Oct;30(5):183-8.
Left ventricular function including regional wall motion (RWM) was evaluated by 99mTc first-pass and equilibrium gated blood pool ventriculography and glycohemoglobin (HbA1c) blood levels determined by a quantitative column technique in 25 young patients with insulin-dependent diabetes mellitus without clinical evidence of heart disease, and in healthy controls matched for age and sex. Phase analysis revealed abnormal RWM in 19 of 21 diabetic patients. The mean left ventricular global ejection fraction, the mean regional ejection fraction and the mean 1/3 filling fraction were lower and the time to peak ejection, the time to peak filling and the time to peak ejection/cardiac cycle were longer in diabetics than in controls. We found high HbA1c levels in all diabetics. There was no significant difference between patients with and without retinopathy and with and without peripheral neuropathy in terms of left ventricular function and HbA1c levels.
通过99mTc首次通过和平衡门控心血池心室造影评估左心室功能，包括局部室壁运动（RWM），并采用定量柱技术测定25例无心脏病临床证据的胰岛素依赖型糖尿病年轻患者以及年龄和性别相匹配的健康对照者的糖化血红蛋白（HbA1c）血水平。相位分析显示，21例糖尿病患者中有19例存在异常的局部室壁运动。糖尿病患者的平均左心室整体射血分数、平均局部射血分数和平均1/3充盈分数较低，射血达峰时间、充盈达峰时间和射血达峰时间/心动周期均比对照组更长。我们发现所有糖尿病患者的HbA1c水平都很高。在左心室功能和HbA1c水平方面，有视网膜病变和无视网膜病变的患者以及有周围神经病变和无周围神经病变的患者之间没有显著差异。
