Magnetic resonance imaging study on spinal cord plasticity in patients with cervical compression myelopathy.

Spinal cord plasticity in 55 patients with cervical compression myelopathy was assessed with magnetic resonance imaging, by which the transverse area of the spinal cord was measured at the site of maximum compression before and after surgery and compared with the conventional modalities of computed tomographic myelography. A high correlation (r = 0.901, P less than 0.01) was observed between the preoperative measurements of magnetic resonance imaging and computed tomographic myelography. The preoperative transverse area was in good correlation with the preoperative Japanese Orthopaedic Association score (r = 0.466, P less than 0.01). In most patients with a spinal cord area of less than 0.45 cm2, the clinical results were poor despite considerable morphologic restoration of the spinal canal obtained after decompression surgery, reflecting an irreversible pathology developed in the spinal cord.