Kurlberg G, Frisk B
Surgical Department, Uddevalla Hospital, Sweden.
Trans R Soc Trop Med Hyg. 1991 Nov-Dec;85(6):793-5. doi: 10.1016/0035-9203(91)90458-b.
A retrospective study of 42 patients treated surgically for typhoid ileal perforation found the mortality to be 24%. The study suggested that general peritonitis was the main cause of death in typhoid ileal perforation. However, the high mortality was significantly improved by adequate preoperative rehydration. The combination of chloramphenicol/gentamicin/metronidazole was superior to other antibiotic regimes. No mortality was recorded with this triple drug therapy.
一项对42例接受手术治疗的伤寒性回肠穿孔患者的回顾性研究发现，死亡率为24%。该研究表明，全身性腹膜炎是伤寒性回肠穿孔的主要死亡原因。然而，术前充分补液可显著降低高死亡率。氯霉素/庆大霉素/甲硝唑联合用药优于其他抗生素治疗方案。采用这种三联药物治疗未记录到死亡病例。
