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[布鲁氏菌病的天然抗性因素]

[Natural resistance factors in brucellosis].

作者信息

Safronova V M, Loktev N A, Liapustina L V, Logvinenko O V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1991 Oct(10):64-5.

PMID:1801494
Abstract

A higher level of the opsono-cytophagous capacity of the blood and the quantitative content of lysosomal cationic proteins in polymorphonuclear neutrophils in the blood of Fischer rats in comparison with the corresponding characteristics in normal guinea pigs has proved to be conductive to more active elimination of the infective agent from the body of the animals after their infection with brucellosis. The indices characterizing the activity and intensity of the phagocytosis of brucellae by polymorphonuclear neutrophils of the blood in combination with the determination of the amount of cationic proteins in these cells permit the objective characterization of the level of nonspecific resistance to brucellosis.

摘要

与正常豚鼠的相应特征相比,费希尔大鼠血液中调理吞噬能力的较高水平以及血液中多形核中性粒细胞中溶酶体阳离子蛋白的定量含量,已被证明有利于动物感染布鲁氏菌病后更积极地从体内清除感染因子。表征血液中多形核中性粒细胞对布鲁氏菌吞噬活性和强度的指标,结合对这些细胞中阳离子蛋白含量的测定,能够客观地表征对布鲁氏菌病的非特异性抵抗力水平。

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