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前列腺癌:2007年的筛查、诊断与管理

Prostate cancer: screening, diagnosis and management in 2007.

作者信息

Grubb Robert L, Kibel Adam S

机构信息

Washington University School of Medicine, St. Louis, USA.

出版信息

Mo Med. 2007 Sep-Oct;104(5):408-13; quiz 413-4.

Abstract

Prostate cancer is the most common solid malignancy in men. Screening with PSA and DRE has led to an increased incidence of the disease, but has also contributed to decreasing mortality. Improved technology has led to treatments focused on maintaining cancer cure rates while minimizing the effect of prostate cancer treatment on quality of life. Recently, docetaxel has been added to standard androgen ablation as an effective treatment for advanced prostate cancer.

摘要

前列腺癌是男性中最常见的实体恶性肿瘤。使用前列腺特异性抗原(PSA)和直肠指检(DRE)进行筛查导致了该疾病发病率的上升,但也有助于降低死亡率。技术的进步使得治疗方法更加注重在维持癌症治愈率的同时,将前列腺癌治疗对生活质量的影响降至最低。最近,多西他赛已被添加到标准雄激素剥夺治疗中,作为晚期前列腺癌的一种有效治疗方法。

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