Endo Keigo
Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Faculty of Medicine.
Nihon Rinsho. 2007 Nov;65(11):2009-15.
Radionuclides are widely used for the diagnosis and therapy of many diseases. Among them, 131I has the longest history of more than 60 years of clinical use, and has been still used for the therapy of Graves' disease, Plummer disease (hyperfunctional adenoma) and thyroid cancer. Radiodine is specifically taken into thyroid cells and organized. Recently PET using 18F-FDG(glucose analogue) is applied to know the extent of thyroid cancer. New tumor specific drugs, such as 131I- or 90Y labeled antibodies, have been discovered and succeeded in the therapy of lymphoma.