Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, University of Bologna, Bologna, Italy.
BioDrugs. 1998 Jun;9(6):477-86. doi: 10.2165/00063030-199809060-00005.
Thymalfasin (thymosin-alpha1) is an immunomodulatory agent that is able to augment some specific T lymphocyte functions, particularly that of promoting the T helper 1 cell responses involved in host antiviral defence. The most promising clinical applications for thymalfasin seem to be as a single agent for the treatment of chronic hepatitis B and in combination with interferon-alpha for the treatment of both chronic hepatitis B and C. These positive preliminary results offer a strong rationale for larger, well-planned clinical trials and also for defining the optimal schedule of administration.
胸腺法新（胸腺肽 α1）是一种免疫调节剂，能够增强某些特定 T 淋巴细胞的功能，特别是促进涉及宿主抗病毒防御的辅助性 T 细胞反应。胸腺法新最有前途的临床应用似乎是作为一种单一药物用于治疗慢性乙型肝炎，以及与干扰素-α联合用于治疗慢性乙型肝炎和丙型肝炎。这些初步的积极结果为更大规模、精心设计的临床试验以及确定最佳给药方案提供了强有力的依据。
