Klein Deborah G
Cardiac Intensive Care Unit and Heart Failure Special Care Unit, Cleveland Clinic, Cleveland, OH, USA.
Crit Care Nurs Clin North Am. 2007 Dec;19(4):445-60, vii. doi: 10.1016/j.ccell.2007.08.001.
More than 30 years of experience in cardiac transplantation have resulted in cardiac transplantation being the primary therapeutic choice for patients under 65 years of age who have advanced heart failure and who remain symptomatic despite maximal medical therapy. The success and widespread use of cardiac transplantation is attributed to more liberal guidelines in recipient and donor selection, effective immunosuppressive therapy, close monitoring for rejection, and effective management of rejection. This article presents the current status of recipient and donor selection, surgical techniques, postoperative care, immunosuppression strategies, and rejection monitoring and management. Challenges associated with allocation of organs continue.
30多年的心脏移植经验使心脏移植成为65岁以下晚期心力衰竭且尽管接受了最大程度药物治疗仍有症状的患者的主要治疗选择。心脏移植的成功及广泛应用归因于受者和供者选择标准更为宽松、有效的免疫抑制治疗、对排斥反应的密切监测以及对排斥反应的有效管理。本文介绍了受者和供者选择、手术技术、术后护理、免疫抑制策略以及排斥反应监测与管理的现状。与器官分配相关的挑战依然存在。
