Gallati H
J Clin Chem Clin Biochem. 1976 Jan;14(1):9-13.
NADH is surprisingly stable, providing it is stored in anhydrous organic solvents, and not, as hitherto, in aqueous solvents. The stability of NADH was investigated in solution in ethylene glycol-Tris over a period of 136 days at temperatures of 2-8 degrees C, 19-22 degrees C, 35 degrees C, 45 degrees C and 60 degrees C. For comparison, the stability of NADH in solution in distilled water was studied under similar conditions.
令人惊讶的是,只要储存在无水有机溶剂中,而不是像迄今为止那样储存在水性溶剂中,NADH就相当稳定。在2至8摄氏度、19至22摄氏度、35摄氏度、45摄氏度和60摄氏度的温度下,对NADH在乙二醇 - 三羟甲基氨基甲烷溶液中的稳定性进行了136天的研究。作为对比,在类似条件下研究了NADH在蒸馏水溶液中的稳定性。