Demir Suleyman, Yilmazturk Gamze Can, Aslan Diler
Pamukkale University, School of Medicine, Department of Biochemistry, Denizli, Turkey.
Diabetes Res Clin Pract. 2008 Mar;79(3):400-4. doi: 10.1016/j.diabres.2007.10.006. Epub 2007 Nov 19.
The objective of this study was to assess accuracy and precision of the Optimum H System for measuring glucose in fresh venous whole blood samples. Ninety-one whole blood specimens were analyzed duplicate on two optimum blood glucose meter and compared to YSI reference analyser and Beckman LX20 laboratory analyser. The study demonstrated that the Optimum H System gives clinically accurate, plasma equivalent glucose results for venous samples, compared to the YSI1.12 reference method. All results were within the clinically acceptable A and B zones of the Parkes error grid, with 98.6% falling within zone A. The mean bias of the Optimum H System versus the YSI1.12 reference was +5.39%, which is consistent with the strip claim that slightly higher results may be observed when using venous samples. The Optimum H System results showed good precision, with an overall mean CV of 3.0%. Plasma results from the Beckman laboratory analyser correlated well with the YSI*1.12 whole blood reference with a slightly higher mean bias of +3.92%. The study demonstrated the Optimum H System to give clinically accurate and precise results for glucose in fresh venous whole blood samples.
本研究的目的是评估Optimum H系统在新鲜静脉全血样本中测量葡萄糖的准确性和精密度。对91份全血标本在两台Optimum血糖仪上进行重复分析，并与YSI参考分析仪和贝克曼LX20实验室分析仪进行比较。研究表明，与YSI1.12参考方法相比，Optimum H系统可为静脉样本提供临床准确的、等同于血浆的葡萄糖结果。所有结果均在Parkes误差网格的临床可接受A区和B区内，98.6%落在A区。Optimum H系统相对于YSI1.12参考的平均偏差为+5.39%，这与试纸条声称使用静脉样本时可能观察到略高的结果一致。Optimum H系统的结果显示出良好的精密度，总体平均变异系数为3.0%。贝克曼实验室分析仪的血浆结果与YSI*1.12全血参考结果相关性良好，平均偏差略高，为+3.92%。该研究表明，Optimum H系统可为新鲜静脉全血样本中的葡萄糖提供临床准确和精确的结果。
