脑膜炎患者脑脊液分离株的抗菌药敏性。

Antimicrobial susceptibility of cerebrospinal isolates from patients with meningitis.

作者信息

Liskova A, Benca J, Kalavsky E, Kovac M, Rudinsky B, Ondrusova A, Kiwou M

机构信息

St Charles Lwanga Clinic, Tropical Project of St Elizabeth University College, Buikwe, Uganda.

出版信息

Neuro Endocrinol Lett. 2007 Nov;28 Suppl 3:5-6.

PMID:18030262

Abstract

Str. pneumoniae isolates were susceptible to penicillin, all to also ofloxacin and chloramphenicol and cefotaxim and 39 (100%) to cotrimoxazol. Concerning S. aureus, all isolates 22 were susceptible to oxacillin and chloramphenicol, and 21 also to cotrimoxazol. All N. meningitidis isolates but one-10 of all were susceptible to penicillin, all to cefotaxim, chloramphenicol and cotrimoxazol. All H.influenzae isolates were susceptible to ampicillin and chloramphenicol, as well as to ofloxacin and cotrimoxazol. Those surprisingly high susceptibilities to rather "old" antibiotics may be explained by low antibiotic consumption, accessibility and therefore low usage which is a key promoter of resistance both in community and hospital.

摘要

肺炎链球菌分离株对青霉素敏感，对氧氟沙星、氯霉素、头孢噻肟也均敏感，39株（100%）对复方新诺明敏感。关于金黄色葡萄球菌，所有22株分离株对苯唑西林和氯霉素敏感，21株对复方新诺明也敏感。除1株外，所有脑膜炎奈瑟菌分离株——全部的10株——对青霉素敏感，对头孢噻肟、氯霉素和复方新诺明均敏感。所有流感嗜血杆菌分离株对氨苄西林、氯霉素、氧氟沙星和复方新诺明均敏感。对这些相当“老”的抗生素出现如此高的敏感性，可能是由于抗生素消耗量低、可及性差，因此使用量低，而这是社区和医院中耐药性的关键促进因素。