Ewe K, Baas E U
Aktuelle Gerontol. 1977 Mar;7(3):135-41.
Geriatric patients are preferentially involved in ischemic bowel disease. The sudden occlusion of the large mesenteric arteries (a. mesenterica superior (more frequently) and inferior) is followed by intestinal gangrene and peritonitis with a poor prognosis and a high letality (greater than 90%). In chronic intestinal ischemia the leading clinical symptom is postprandial pain ('claudicatio intestinalis'). In some cases of acute mesenteric artery occlusion no embolus or thrombus will be found. In these cases the circulation in the arteriosclerotic vessels falls below a critical value due to cardiac insufficiency, shock, digitalis overdose and others. In less severe ischemia the mucosa is involved being most sensitive to O2 deprivation. It usually regenerates within a few days. This form is found more frequently in the colon than in other parts of the gut (about 40%): ischemic colitis. The therapy - if possible in acute, fulminant ischemia or if necessary in chronic intestinal ischemia - is surgical consisting in reconstructive procedures of the mesenteric circulation.
老年患者更容易患缺血性肠病。肠系膜大动脉(更常见的是肠系膜上动脉,较少见的是肠系膜下动脉)突然闭塞后会导致肠坏疽和腹膜炎,预后较差,死亡率很高(超过90%)。在慢性肠缺血中,主要的临床症状是餐后疼痛(“肠间歇性跛行”)。在某些急性肠系膜动脉闭塞的病例中,找不到栓子或血栓。在这些情况下,由于心功能不全、休克、洋地黄过量等原因,动脉硬化血管中的循环低于临界值。在不太严重的缺血情况下,黏膜受累,对缺氧最为敏感。它通常在几天内再生。这种形式在结肠中比在肠道的其他部位更常见(约40%):缺血性结肠炎。治疗方法——如果可能,用于急性暴发性缺血;如果必要,用于慢性肠缺血——是手术治疗,包括肠系膜循环的重建手术。