["阿司匹林" 支气管哮喘患者血小板功能活性特征]
[Characteristics of functional activity of thrombocytes in patients with "aspirin" bronchial asthma].
作者信息
Evsiukova E V
出版信息
Klin Med (Mosk). 1991 Sep;69(9):26-9.
PMID:1803142
Abstract
Upon comparison of functional activity of platelets and their response to aspirin in 20 subjects with aspirin bronchial asthma, 19 patients with non-aspirin bronchial asthma and 21 healthy controls it was found out that in aspirin asthma platelet count is elevated, their response to aggregation inductors enhances while to aspirin is abnormal, plasmic thromboxane level is reduced. Aspirin asthma patients are believed to have a specific platelet defect.
摘要
在对20名阿司匹林性支气管哮喘患者、19名非阿司匹林性支气管哮喘患者和21名健康对照者的血小板功能活性及其对阿司匹林的反应进行比较时，发现阿司匹林哮喘患者的血小板计数升高，其对聚集诱导剂的反应增强，而对阿司匹林的反应异常，血浆血栓素水平降低。阿司匹林哮喘患者被认为存在特定的血小板缺陷。
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