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Measurement of binding anti-IFNbeta antibodies in IFNbeta-treated MS patients: lessons for the clinician and basic scientist.

作者信息

Pachner Andrew R

出版信息

J Neuroimmunol. 2008 Feb;194(1-2):5-6. doi: 10.1016/j.jneuroim.2007.10.015. Epub 2007 Nov 26.

DOI:10.1016/j.jneuroim.2007.10.015
PMID:18031830
Abstract
摘要

相似文献

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Measurement of binding anti-IFNbeta antibodies in IFNbeta-treated MS patients: lessons for the clinician and basic scientist.干扰素β治疗的多发性硬化症患者中抗干扰素β结合抗体的检测：给临床医生和基础科学家的启示
J Neuroimmunol. 2008 Feb;194(1-2):5-6. doi: 10.1016/j.jneuroim.2007.10.015. Epub 2007 Nov 26.
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Measurement of neutralizing antibodies to interferon beta in patients with multiple sclerosis.多发性硬化症患者中干扰素β中和抗体的检测
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Persistency of neutralizing antibodies depends on titer and interferon-beta preparation.中和抗体的持久性取决于效价和干扰素-β制剂。
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Anti-interferon-beta neutralising activity is not entirely mediated by antibodies.抗干扰素-β中和活性并非完全由抗体介导。
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Development and validation of a real time PCR-based bioassay for quantification of neutralizing antibodies against human interferon-beta.一种基于实时PCR的生物测定法的开发与验证，用于定量检测抗人干扰素-β的中和抗体。
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The importance of measuring IFNbeta bioactivity: monitoring in MS patients and the effect of anti-IFNbeta antibodies.测量干扰素β生物活性的重要性：对多发性硬化症患者的监测及抗干扰素β抗体的影响
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Interferon beta preparations for the treatment of multiple sclerosis patients differ in neutralizing antibody seroprevalence and immunogenicity.用于治疗多发性硬化症患者的β-干扰素制剂在中和抗体血清阳性率和免疫原性方面存在差异。
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Neutralising antibodies against interferon beta in multiple sclerosis.多发性硬化症中针对β干扰素的中和抗体。
Lancet. 2004 Jan 10;363(9403):168; author reply 168-9. doi: 10.1016/S0140-6736(03)15277-4.

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