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迈向日本癌症疼痛的缓解

Toward freedom from cancer pain in Japan.

作者信息

Otsuka Kuniko, Yasuhara Hajime

机构信息

Department of Pharmacology, Showa University School of Medicine, Tokyo, Japan.

出版信息

J Pain Palliat Care Pharmacother. 2007;21(3):37-42.

Abstract

Life expectancy in Japan is highest in the world. Cancer is the leading cause of mortality in Japan, accounting for about 30 percent of all deaths. Many Japanese cancer patients experience severe pain although they and their families hope to be pain free at the end of their lives. Toward that end, the consumption of morphine in Japan has increased markedly since 1989. The amount of morphine hydrochloride and morphine sulfate consumed in 2001 was 6.1 times that used in Japan in 1989. However, the amount of morphine consumed in Japan is still less than in other developed nations, and was only one-sixth of the amount used in Australia in 2001. As a result, many Japanese cancer patients experience potentially manageable cancer pain, largely because the amount of the drug used by doctors is insufficient for pain control. An increasing number of Japanese doctors now understand that their patients' quality of life is most important in end-of-life care and how to use the three step analgesic ladder of the World Health Organization (WHO). However, other doctors do not understand these issues sufficiently causing some patients to die without good pain control. Both the general population and some medical professionals misunderstand and have prejudice against the use of morphine. Patients often do not participate in decision making about medical treatment because of remaining paternalism in the relationship between Japanese doctors and patients. Thus, cancer pain management in Japan is not as effective as it can be and not all Japanese cancer patients receive appropriate management for their cancer pain. To improve outcomes for Japanese patients, it is necessary for health professional and social work students and practicing professionals to receive contemporary education including an introduction to palliative care and ethics.

摘要

日本的预期寿命位居世界之首。癌症是日本的主要死因,约占所有死亡人数的30%。许多日本癌症患者经历着剧痛,尽管他们及其家人希望在生命终结时免受疼痛折磨。为此,自1989年以来,日本吗啡的消费量显著增加。2001年盐酸吗啡和硫酸吗啡的消费量是1989年日本消费量的6.1倍。然而,日本的吗啡消费量仍低于其他发达国家,2001年仅为澳大利亚消费量的六分之一。结果,许多日本癌症患者遭受着本可控制的癌症疼痛,主要原因是医生使用的药物量不足以控制疼痛。越来越多的日本医生现在明白,在临终关怀中患者的生活质量最为重要,以及如何使用世界卫生组织(WHO)的三阶梯镇痛法。然而,其他医生对这些问题的理解不够充分,导致一些患者在疼痛未得到有效控制的情况下死亡。普通民众和一些医学专业人员对吗啡的使用存在误解和偏见。由于日本医患关系中残留的家长式作风,患者往往不参与医疗决策。因此,日本的癌症疼痛管理未能达到应有的效果,并非所有日本癌症患者都能得到适当的癌症疼痛管理。为改善日本患者的治疗效果,卫生专业和社会工作专业的学生以及在职专业人员有必要接受包括姑息治疗和伦理学入门在内的当代教育。

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