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一项关于患者对停用长期选择性5-羟色胺再摄取抑制剂看法的定性研究。

A qualitative study of patient views on discontinuing long-term selective serotonin reuptake inhibitors.

作者信息

Leydon Geraldine M, Rodgers Lynne, Kendrick Tony

机构信息

Primary Medical Care, Community Clinical Sciences Division, University of Southampton School of Medicine, Aldermoor Health Centre, Aldermoor Close, Southampton SO16 5ST, UK.

出版信息

Fam Pract. 2007 Dec;24(6):570-5. doi: 10.1093/fampra/cmm069. Epub 2007 Nov 20.

Abstract

BACKGROUND

There is concern that patients may be remaining on selective serotonin reuptake inhibitors (SSRIs) longer than is clinically indicated. Previous research has explored patients' experiences of taking SSRIs and decisions about starting medication. There has been less research into patients' reasons for long-term use and their views and experiences of discontinuation.

AIM

To explore patient experiences of and beliefs about their long-standing SSRI use and understand the barriers and facilitators to discontinuation.

DESIGN

Face-to-face semi-structured qualitative interview study.

SETTING

One group general practice in Southampton, UK.

FINDINGS

Three overarching themes were identified: (i) patient uncertainty about the benefits of, and continued need for, SSRI medication; (ii) barriers to stopping, including fear of withdrawal symptoms and fear of relapse; and (iii) the importance of the GP's role in facilitating cessation. Uncertainty and fear about withdrawal symptoms and what patients would be like without their medication were key barriers to stopping, even among patients who felt no discernible benefit from taking SSRIs. Patients indicated a need to share the decision to stop with their GP. However, the majority of patients interviewed had received repeat prescriptions of SSRIs without being reviewed by the GP.

CONCLUSIONS

Patients prescribed SSRI medication need to be reassured that, as with starting medication, thinking about or actually stopping medication is a task that will not be managed in isolation, but with the support of their GP.

摘要

背景

人们担心患者服用选择性5-羟色胺再摄取抑制剂(SSRI)的时间可能超过临床指征。以往研究探讨了患者服用SSRI的经历以及开始用药的决定。对于患者长期用药的原因以及他们对停药的看法和经历的研究较少。

目的

探讨患者长期使用SSRI的经历和信念,并了解停药的障碍和促进因素。

设计

面对面半结构化定性访谈研究。

地点

英国南安普敦的一家全科诊所。

结果

确定了三个总体主题:(i)患者对SSRI药物益处和持续需求的不确定性;(ii)停药障碍,包括对戒断症状的恐惧和对复发的恐惧;(iii)全科医生在促进停药方面作用的重要性。对戒断症状以及停药后自身状况的不确定性和恐惧是停药的关键障碍,即使是那些认为服用SSRI没有明显益处的患者也是如此。患者表示需要与全科医生共同做出停药决定。然而,大多数接受访谈的患者在未经过全科医生复查的情况下就收到了SSRI的重复处方。

结论

需要向开具SSRI药物的患者保证,与开始用药一样,考虑或实际停药并非孤立进行的任务,而是需要全科医生的支持。

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