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[结核菌素疗法对青少年肺结核患者免疫指标的影响]

[The effect of tuberculin therapy on immunologic indicators in adolescents with pulmonary tuberculosis].

作者信息

Knoring B E, Pavlova M V, Ivanova L A

出版信息

Probl Tuberk. 1991(12):31-4.

PMID:1803370
Abstract

Study of a combination of immunologic parameters in 29 adolescents with pulmonary tuberculosis who were subject to a combined treatment with the use of tuberculin demonstrated a decline in heightened specific cellular sensitivity, enhancement of antituberculous antibodies synthesis, normalization of the content and functional activity of T- and B-lymphocytes and rise of the level of class G and M immunoglobulins. It has been concluded that tuberculin has a desensitizing action combined with simultaneous stimulation of humoral response and the normalizing action on the T-lymphocyte system.

摘要

对29名接受结核菌素联合治疗的青少年肺结核患者的免疫参数组合进行研究,结果显示,其增强的特异性细胞敏感性有所下降,抗结核抗体合成增强,T淋巴细胞和B淋巴细胞的含量及功能活性恢复正常,G类和M类免疫球蛋白水平升高。得出的结论是,结核菌素具有脱敏作用,同时刺激体液反应,并对T淋巴细胞系统具有正常化作用。

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