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[2002年巴西里约热内卢市的空气污染与低出生体重]

[Air pollution and low birth weight in the city of Rio de Janeiro, Brazil, 2002].

作者信息

Junger Washington Leite, Leon Antonio Ponce de

机构信息

Instituto de Medicina Social, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil.

出版信息

Cad Saude Publica. 2007;23 Suppl 4:S588-98. doi: 10.1590/s0102-311x2007001600019.

Abstract

The objective of this study was to evaluate the effect of air pollution on low birth weight in full term singleton newborns in the city of Rio de Janeiro, Brazil. The study adopted a cross-sectional design based on the year 2002. Data on live births were obtained from the Live Birth Information System of the Brazilian Ministry of Health. Low birth weight was defined as less than 2,500 g. Maternal exposure to air pollution was defined as the mean for a given pollutant over each trimester of pregnancy and was assessed taking birth date into account. Adjusted odds ratios (OR) were estimated for each potential risk factor. For PM(10), CO, and NO(2), no significant increases were detected. For SO(2), the OR of the fourth interquartile range of exposure in the third trimester of pregnancy was 1.149 (95%CI: 1.016-1.301). For O(3), the estimated OR was 0.830 (95%CI: 0.750-0.987). When exposure variable was regarded as a continuous measure, the OR for PM(10), CO, and SO2 in the third trimester were not statistically significant and were 1.089, 2.223, and 1.259, respectively.

摘要

本研究的目的是评估巴西里约热内卢市空气污染对足月单胎新生儿低出生体重的影响。该研究采用了基于2002年的横断面设计。活产数据来自巴西卫生部的活产信息系统。低出生体重定义为低于2500克。孕妇空气污染暴露定义为孕期各阶段特定污染物的平均值,并在考虑出生日期的情况下进行评估。对每个潜在风险因素估计调整后的优势比(OR)。对于PM(10)、CO和NO(2),未检测到显著增加。对于SO(2),孕期第三个阶段暴露的第四个四分位数区间的OR为1.149(95%CI:1.016 - 1.301)。对于O(3),估计的OR为0.830(95%CI:0.750 - 0.987)。当将暴露变量视为连续测量时,孕期第三个阶段PM(10)、CO和SO2的OR无统计学意义,分别为1.089、2.223和1.259。

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