Requia Weeberb J, Amini Heresh, Adams Matthew D, Schwartz Joel D
School of Public Policy and Government, Fundação Getúlio Vargas, Brasília, Distrito Federal, Brazil.
Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Lancet Reg Health Am. 2022 Mar 15;11:100229. doi: 10.1016/j.lana.2022.100229. eCollection 2022 Jul.
Air pollution exposure has been associated with critical neonatal morbidities, including low birth weight (LBW). However, little is known on short-term exposure to wildfire smoke and LBW. In this study, we estimated the association between birth weight following pregnancy and wildfire smoke exposure in more than 1.5 million newborns in Brazil (considered as a very fire-prone region worldwide).
We applied a logistic regression model to estimate the percent variation in newborns with low birth weight when exposed to wildfire in different trimesters of the pregnancy.
After adjusting the model with relevant covariates, we found that an increase of 100 wildfire records in Brazil was associated with an increase in low birth weight in the Midwest region [0.98% (95%CI:0.34; 1.63)] and in the South region [18.55% (95%CI:13.66; 23.65)] when the exposure occurred in the first trimester of pregnancy.
Wildfires were associated with LBW and this should be of public health concern for policymakers.
Brazilian Agencies National Council for Scientific and Technological Development (CNPq); Ministry of Science, Technology and Innovation in Brazil (MCTI); and Novo Nordisk Foundation Challenge Programme.
空气污染暴露与包括低出生体重（LBW）在内的新生儿严重发病情况有关。然而，关于短期暴露于野火烟雾与低出生体重之间的关系知之甚少。在本研究中，我们估计了巴西超过150万新生儿（巴西被认为是全球野火高发地区）孕期接触野火烟雾与出生体重之间的关联。
我们应用逻辑回归模型来估计孕期不同阶段暴露于野火时低出生体重新生儿的百分比变化。
在对模型进行相关协变量调整后，我们发现，当孕期首月暴露于野火时，巴西野火记录增加100条与中西部地区低出生体重增加[0.98%（95%置信区间：0.34；1.63）]以及南部地区低出生体重增加[18.55%（95%置信区间：13.66；23.65）]相关。
野火与低出生体重有关，这应引起政策制定者对公共卫生的关注。
巴西机构国家科学技术发展委员会（CNPq）；巴西科学、技术和创新部（MCTI）；以及诺和诺德基金会挑战计划。
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