López Ariztegui N, Mondéjar Marín B, García Montero R
Servicio de Neurología. Hospital Virgen de la Salud. Toledo.
Neurologia. 2007 Dec;22(10):906-10.
Acute transverse myelitis is an acute or subacute disorder of the spinal cord resulting in motor, sensory and sphincter dysfunction secondary to various causes.
We present a 32 year-old female patient with an acute episode of bladder dysfunction and fever, followed by motor and sensory dysfunction in legs with sensory spinal level at D2-D3, two weeks after an eutocic delivery with uncomplicated epidural anesthesia. The cerebrospinal fluid (CSF) showed mild lymphocytic pleocytosis, high protein levels with normal glucose concentration, absence of oligoclonal bands and negative serum and CSF virology screening. The cervicodorsal magnetic resonance imaging showed widening of the spinal cord with diffuse patchy hyperintensity on the C6-D1 and D2-D5 levels without contrast enhancement. The patient was treated with intravenous high doses of methylprednisolone with favorable outcome and complete recovery within one year and no relapses two years after the episode.
The main etiologies of non-compressive acute myelopathy as multiple sclerosis, systemic diseases, spinal cord infarct and direct infections have been ruled out with the complementary examinations. We consider that our patient had a parainfectious acute transverse myelitis and epidural anesthesia could be an incidental but possible contributing factor.
急性横贯性脊髓炎是一种脊髓的急性或亚急性疾病,继发于各种病因,导致运动、感觉和括约肌功能障碍。
我们报告一名32岁女性患者,在顺产并接受无并发症的硬膜外麻醉两周后,出现膀胱功能障碍和发热的急性发作,随后出现腿部运动和感觉功能障碍,感觉平面位于D2 - D3。脑脊液显示轻度淋巴细胞增多,蛋白水平升高,葡萄糖浓度正常,无寡克隆带,血清和脑脊液病毒学筛查均为阴性。颈胸段磁共振成像显示脊髓增宽,在C6 - D1和D2 - D5水平有弥漫性斑片状高信号,无强化。患者接受了大剂量静脉注射甲基强的松龙治疗,预后良好,一年内完全康复,发作两年后无复发。
通过辅助检查排除了非压迫性急性脊髓病的主要病因,如多发性硬化、全身性疾病、脊髓梗死和直接感染。我们认为我们的患者患有感染后急性横贯性脊髓炎,硬膜外麻醉可能是一个偶然但可能的促成因素。