Etoh Seiji, Kawahira Kazumi, Ogata Atsuko, Shimodozono Megumi, Tanaka Nobuyuki
Department of Rehabilitation and Physical Medicine, Faculty of Medicine, Kagoshima University, Kirishima-city, Kagoshima, Japan.
Int J Neurosci. 2008 Jan;118(1):137-47. doi: 10.1080/00207450601044686.
This study investigated the relationship between dysgeusia and dysesthesia in stroke patients and evaluated the effect of carbamazepine therapy. Twenty-four patients with dysesthesia of the face, oral cavity, or tongue were divided into two groups: with and without subjective dysgeusia. Taste thresholds were objectively evaluated using the filter-paper taste test and electrogustometry. There was no significant difference in taste thresholds between the two groups. Carbamazepine had an effect on subjective dysgeusia in four of the eight treated patients. Dysgeusia with dysesthesia in stroke patients might be caused by disorders of the somatosensory pathway rather than disorders of the gustatory pathway.
本研究调查了中风患者味觉障碍与感觉异常之间的关系,并评估了卡马西平治疗的效果。24名面部、口腔或舌部感觉异常的患者被分为两组:有和没有主观味觉障碍。使用滤纸味觉测试和电味觉测量法客观评估味觉阈值。两组之间的味觉阈值没有显著差异。在8名接受治疗的患者中,有4名患者的主观味觉障碍对卡马西平有反应。中风患者的味觉障碍伴感觉异常可能是由躯体感觉通路紊乱而非味觉通路紊乱引起的。