硝唑尼特：一种广谱抗感染药物的临床研究
Nitazoxanide: clinical studies of a broad-spectrum anti-infective agent.
作者信息
Aslam Saima, Musher Daniel M
机构信息
Michael E DeBakey VA Medical Center, Section of Infectious Diseases, Room 4B-370, 2002 Holcombe Blvd, Houston, TX 77030, USA.
出版信息
Future Microbiol. 2007 Dec;2(6):583-90. doi: 10.2217/17460913.2.6.583.
Nitazoxanide is a new compound with broad-spectrum activity against numerous intestinal protozoa, helminths and anaerobic bacteria. It is approved for the treatment of diseases caused by Giardia intestinalis and Cryptosporidium species. The drug is well tolerated, with few side effects and requires a short course of treatment. Further investigations regarding its use in patients with AIDS is needed. Nitazoxanide represents a significant advance in the treatment of intestinal parasitic infections worldwide.
硝唑尼特是一种新型化合物，对多种肠道原生动物、蠕虫和厌氧菌具有广谱活性。它已被批准用于治疗由肠道贾第虫和隐孢子虫属引起的疾病。该药物耐受性良好，副作用少，且疗程短。还需要进一步研究其在艾滋病患者中的应用。硝唑尼特在全球肠道寄生虫感染的治疗方面代表了一项重大进展。
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