Ginsberg Gregory G
Am J Gastroenterol. 2007 Dec;102(12):2678-9. doi: 10.1111/j.1572-0241.2007.01557.x.
Advanced esophageal carcinoma has a rather dismal prognosis with dysphagia to solids and liquids as a common symptom. Self-expanding metal stents provide immediate and durable relief of dysphagia. Recently, self-expanding plastic stents have been developed for refractory benign esophageal strictures but may have applications in malignant strictures as well. In this issue of The American Journal of Gastroenterology, a multicenter, prospective, randomized, comparative trial evaluates the safety and efficacy of self-expanding metal versus plastic stents for palliation of dysphagia due to esophageal cancer. While the stents compared equivalently for symptom relief, complications were observed more commonly in the plastic stent group.
晚期食管癌预后相当不佳，吞咽固体和液体困难是其常见症状。自膨式金属支架能立即且持久地缓解吞咽困难。近来，自膨式塑料支架已被研发用于难治性良性食管狭窄，不过在恶性狭窄中或许也有应用。在本期《美国胃肠病学杂志》中，一项多中心、前瞻性、随机、对照试验评估了自膨式金属支架与塑料支架缓解食管癌所致吞咽困难的安全性和有效性。虽然在缓解症状方面两种支架效果相当，但塑料支架组观察到的并发症更为常见。
