Azak Alper, Oksüzoğlu Berna, Deren Tağmaç, Oneç Birgül Müftüoğlu, Zengin Nurullah
Department of Internal Medicine, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Anticancer Drugs. 2008 Jan;19(1):97-8. doi: 10.1097/CAD.0b013e3282f0777e.
Even though testicular nonseminomatous germ cell tumors (NSGCTs) usually have a good prognosis and high curability rates, unpredicted complications owing to chemotherapy regimens might complicate the course. Modalities that are commonly used to cure NSGCTs have well-known side effects. Thromboembolism, which is infrequently associated with germ cell tumors and the vascular toxicity of chemotherapeutics, causes morbidity and mortality. We report a young testicular NSGCT patient, without any known underlying risk factor, who experienced an unpredicted cerebrovascular accident after he received cisplatin-based combination chemotherapy.
尽管睾丸非精原细胞性生殖细胞肿瘤(NSGCTs)通常预后良好且治愈率高,但化疗方案引发的意外并发症可能会使病程复杂化。常用于治愈NSGCTs的治疗方法有众所周知的副作用。血栓栓塞很少与生殖细胞肿瘤及化疗药物的血管毒性相关,但会导致发病和死亡。我们报告一名年轻的睾丸NSGCT患者,他没有任何已知的潜在风险因素,在接受基于顺铂的联合化疗后发生了意外的脑血管意外。