Yuan X, Chen M
PUMC Hospital, CAMS, Beijing.
Chin Med Sci J. 1991 Jun;6(2):107-9.
Forty cases of overlap syndrome of progressive systemic sclerosis and polymyositis (OS PSS-PM) are reported in this paper. All of these cases had manifestations of both PSS and PM as well as Raynaud's phenomenon. The sclerodermatous skin changes were diffused over the whole body in most cases. All cases had muscular weakness, elevated skeletal muscle enzyme levels and muscle damage as seen on the electromyogram. Histopathologic changes showed characteristics of myositis. There was noticeable systemic involvement, especially with the digestive and circulatory systems. Serologic examination frequently revealed autoantibodies. The patients responded well to traditional Chinese medicines and corticosteroids.
本文报告了40例进行性系统性硬化症与多发性肌炎重叠综合征（OS PSS-PM）。所有这些病例均有PSS和PM的表现以及雷诺现象。大多数病例中硬皮病样皮肤改变遍布全身。所有病例均有肌无力、骨骼肌酶水平升高以及肌电图显示的肌肉损伤。组织病理学改变显示为肌炎特征。有明显的全身受累，尤其是消化系统和循环系统。血清学检查常发现自身抗体。患者对中药和皮质类固醇反应良好。
