Tu S X
Health and Anti-epidemic Center, Xinyang District.
Zhonghua Fu Chan Ke Za Zhi. 1991 Nov;26(6):358-60, 388.
A survey of hepatitis B virus infection was carried out among 1,947 pregnant women. The results showed that 215 women were HBsAg positive, a rate of 10.7%. Among the 38 serum samples reexamined, 10 were positive both for HBsAg and HBeAg (26.3%). In order to evaluate the effect of hepatitis B vaccine on inhibiting vertical transmission, all infants of the 38 women positive for HBsAg were given hepatitis B vaccine 40 micrograms. by injection 7 months after the immunization, HBsAg was found absent in 31 of them, but all the infants had produced anti-HBsAg antibody. The positive rate of anti-HBsAg antibody in infants whose mothers had both positive HBsAg and HBeAg was 50%, whereas in infants whose mothers had only positive HBsAg it was 92.9% (chi 2 = 6.38 P less than 0.05).
对1947名孕妇进行了乙肝病毒感染情况调查。结果显示，215名妇女HBsAg呈阳性，阳性率为10.7%。在重新检测的38份血清样本中，10份HBsAg和HBeAg均为阳性（26.3%）。为评估乙肝疫苗对抑制垂直传播的效果，对38名HBsAg呈阳性的妇女所生的所有婴儿均接种40微克乙肝疫苗。免疫7个月后进行注射，发现其中31名婴儿HBsAg呈阴性，但所有婴儿均产生了抗-HBsAg抗体。母亲HBsAg和HBeAg均呈阳性的婴儿中抗-HBsAg抗体阳性率为50%，而母亲仅HBsAg呈阳性的婴儿中该阳性率为92.9%（χ2 = 6.38，P < 0.05）。
