Collier Lara S, Largaespada David A
The Department of Genetics, Cell Biology and Development, The Cancer Center, The University of Minnesota Twin Cities, Church St SE, Minneapolis, Minnesota 55455, USA.
Genome Biol. 2007;8 Suppl 1(Suppl 1):S5. doi: 10.1186/gb-2007-8-s1-s5.
Although alterations in the genomes of somatic cells cannot be passed on to future generations, they can have beneficial or detrimental effects on the host organism, depending on the context in which they occur. This review outlines the ways in which transposable elements have important consequences for somatic cell genomes.
虽然体细胞基因组的改变不能传递给后代,但根据其发生的背景,它们可能对宿主生物体产生有益或有害的影响。本综述概述了转座元件对体细胞基因组产生重要影响的方式。