老鹳草素对巨噬细胞形态和功能的影响。
Effects of geraniin on morphology and function of macrophages.
作者信息
Ushio Y, Okuda T, Abe H
机构信息
Research Institute of Oriental Medicine, Kinki University, Osaka, Japan.
出版信息
Int Arch Allergy Appl Immunol. 1991;96(3):224-30. doi: 10.1159/000235499.
PMID:1804795
Abstract
The effects of geraniin, a tannin, isolated from Geranium thunbergii Sieb. et Zucc. on the morphology and function of macrophages were studied. Geraniin caused a marked retardation of the recovery from fully spread surface membrane and a highly reorganized cytoskeleton of macrophages, whereas endocytotic activity, phagocytosis and pinocytosis in the cells were significantly inhibited.
摘要
研究了从日本老鹳草中分离得到的一种单宁——老鹳草素对巨噬细胞形态和功能的影响。老鹳草素导致巨噬细胞从完全伸展的表面膜恢复的过程明显延迟，且细胞骨架高度重组，而细胞内的内吞活性、吞噬作用和胞饮作用均受到显著抑制。
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