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脆性骨折患者的骨质疏松症疾病管理:基于三年骨质疏松症护理服务经验的新认识

Osteoporosis disease management for fragility fracture patients: new understandings based on three years' experience with an osteoporosis care service.

作者信息

Harrington J Timothy, Lease JoEllen

机构信息

University of Wisconsin School of Medicine and Public Health, Madison, WI 53715, USA.

出版信息

Arthritis Rheum. 2007 Dec 15;57(8):1502-6. doi: 10.1002/art.23093.

Abstract

OBJECTIVE

To review the 3-year performance of an established osteoporosis care service and consider further improvements in an effort to reduce fragility fractures.

METHODS

Osteoporosis care has been coordinated for all willing and able patients with orthopedic fragility fractures in our health system by a nurse and medical director since 2003, using a guideline-based care algorithm and task management software. Patients were followed by telephone for 2 years to monitor their status and optimize adherence to treatment. Demographics, management recommendations, clinical data, and adherence to treatment were reviewed for the 2003-2005 patient population.

RESULTS

Of 1,019 patients with fragility fractures, 61% underwent osteoporosis evaluation and treatment. The remainder included 15% who refused to participate and 24% who were unable to participate for various logistical and health reasons. More patients age >80 years were unwilling or unable to participate. Bone densities (dual x-ray absorptiometry [DXA]) were normal, low, or osteoporotic in 24%, 55%, and 21% of patients, respectively, and 60% of the osteoporotic group had > or = 1 abnormal metabolic bone laboratory result. Only 17% of the total reported a previous fracture, and 47% had ever undergone DXA. Few experienced bone loss, a new fracture, or bisphosphonate intolerance during treatment.

CONCLUSION

An osteoporosis care service has coordinated care for every willing and able fragility fracture patient with positive outcomes. In addition, the results suggest a high priority for earlier proactive diagnosis and intervention of the at-risk population if fractures are to be reduced.

摘要

目的

回顾一项成熟的骨质疏松症护理服务的三年运行情况,并考虑进一步改进以减少脆性骨折。

方法

自2003年起,在我们的医疗系统中,由一名护士和医疗主任为所有愿意且能够接受治疗的骨科脆性骨折患者协调骨质疏松症护理,采用基于指南的护理算法和任务管理软件。通过电话随访患者2年,以监测其状况并优化治疗依从性。对2003 - 2005年患者群体的人口统计学、管理建议、临床数据和治疗依从性进行了回顾。

结果

在1019例脆性骨折患者中,61%接受了骨质疏松症评估和治疗。其余患者包括15%拒绝参与和24%因各种后勤和健康原因无法参与的患者。年龄>80岁的患者中,更多人不愿意或无法参与。患者的骨密度(双能X线吸收法[DXA])分别有24%正常、55%低骨量或21%骨质疏松,骨质疏松组中60%有≥1项代谢性骨实验室检查结果异常。总共只有17%的患者报告有既往骨折史,47%的患者曾接受过DXA检查。治疗期间很少有人出现骨质流失、新发骨折或双膦酸盐不耐受情况。

结论

一项骨质疏松症护理服务已为每一位愿意且能够接受治疗的脆性骨折患者协调了护理,取得了积极成果。此外,结果表明,如果要减少骨折,对高危人群进行早期主动诊断和干预具有高度优先性。

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