Peña H G, Kessler W V, Christian J E, Cline T R, Plumlee M P
Poult Sci. 1976 Jan;55(1):188-201. doi: 10.3382/ps.0550188.
The concentrations of 36Cl-labeled potassium perchlorate (K36CiO4) and previously reported iodide (131I) in the ova, thyroid gland, and blood of the laying hen were compared in this investigation. Radioperchlorate concentration and deposition properties showed a remarkable resemblance to those of iodide (131I). The topographic distribution of radioperchlorate in ova followed a peripheral and concentric ring deposition identical to that observed in the 131I investigation. The studies of the distribution of radioperchlorate showed that about 10.3, 2.0, and 1.4% of a single intramuscular injection of K36CiO4 was retained in the body at 3, 24, and 48 hours, respectively. The largest total concentration in the 3-hour group was found in the blood (2.9%), followed by muscles (2.4%), internal organs (1.1%), and the 10 largest ova (1.0%). The 24 and 48-hour hens' ova showed the largest concentrations with values of 1.5 and 1.2% of the dose, respectively. This represented 76.9 and 81.3% of the total activity retained in the body at these times. The excreta in the 3 and 24-hour experiments accounted for most of the radioperchlorate dose.
本研究比较了产蛋母鸡的卵、甲状腺和血液中36Cl标记的高氯酸钾（K36CiO4）的浓度以及先前报道的碘化物（131I）的浓度。放射性高氯酸盐的浓度和沉积特性与碘化物（131I）的显著相似。卵中放射性高氯酸盐的地形分布遵循与131I研究中观察到的相同的外周和同心环沉积模式。放射性高氯酸盐分布的研究表明，单次肌肉注射K36CiO4后，在3、24和48小时时分别约有10.3%、2.0%和1.4%保留在体内。3小时组中总浓度最高的是血液（2.9%），其次是肌肉（2.4%）、内脏器官（1.1%）和10个最大的卵（1.0%）。24小时和48小时母鸡的卵中浓度最高，分别为剂量的1.5%和1.2%。这分别占此时体内保留的总活性的76.9%和81.3%。3小时和24小时实验中的排泄物占放射性高氯酸盐剂量的大部分。
