Tokuyasu Hirokazu, Watanabe Etsuko, Okazaki Ryota, Touge Hirokazu, Kawasaki Yuji, Isowa Noritaka, Eiji Shimizu
Divisions of Respiratory Medicine, Matsue Red Cross Hospital.
Nihon Kokyuki Gakkai Zasshi. 2007 Nov;45(11):884-9.
We report a rare case of tuberculous pleurisy with a rapid decrease in pleural effusion by levofloxacin. A 73-year-old woman admitted due to dyspnea on exertion of one month duration. She had aortitis syndrome which had been treated with oral prednisolone for 6 months. Chest roentgenogram showed left pleural effusion, which was exudative with lymphocyte predominance and an increased level of adenosine deaminase. One-week administration of levofloxacin remarkably decreased effusion. as demonstrated on chest roentgenogram 2 weeks after treatment. Since Mycobacterium tuberculosis was isolated in culture from bronchial lavage fluid and sputum, we prescribed antituberculous therapy with isoniazid, rifampicin and ethambutol. resulting in complete resolution.
我们报告一例罕见的结核性胸膜炎,左氧氟沙星治疗后胸腔积液迅速减少。一名73岁女性因持续1个月的劳力性呼吸困难入院。她患有主动脉炎综合征,已口服泼尼松龙治疗6个月。胸部X线片显示左侧胸腔积液,为渗出液,淋巴细胞为主,腺苷脱氨酶水平升高。左氧氟沙星治疗1周后胸腔积液明显减少,治疗2周后的胸部X线片显示了这一情况。由于支气管灌洗液和痰液培养分离出结核分枝杆菌,我们给予异烟肼、利福平及乙胺丁醇抗结核治疗,最终积液完全消退。