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95岁人群样本中的精神病症状和偏执观念

Psychotic symptoms and paranoid ideation in a population-based sample of 95-year-olds.

作者信息

Ostling Svante, Börjesson-Hanson Anne, Skoog Ingmar

机构信息

Sahlgrenska Academy at Göteborg University, Institute of Neuroscience and Physiology, Psychiatry, and Neurochemistry Section, Sahlgrenska University Hospital, Göteborg, Sweden.

出版信息

Am J Geriatr Psychiatry. 2007 Dec;15(12):999-1004. doi: 10.1097/JGP.0b013e31814622b9.

Abstract

OBJECTIVE

To examine the 1-year prevalence of psychotic symptoms and schizophrenia in nondemented 95-year-olds, and to examine the relation between psychotic symptoms and other psychiatric symptoms, sensory impairments, and cognitive functioning.

PARTICIPANTS

The representative sample was 95-year-olds living in Göteborg, Sweden (N = 338). Individuals with dementia were excluded (N = 175), leaving 163 subjects for this study.

DESIGN

This was a cross-sectional population study, including psychiatric and physical examinations, cognitive tests, and interviews with close informants.

MEASUREMENTS

Diagnosis of schizophrenia, psychotic symptoms, paranoid ideation and dementia according to Diagnostic and Statistical Manual of Mental Disorders, Third Revision (DSM-III) were measured. Cognitive function was tested with the Mini-Mental State Exam. Other psychiatric symptoms were measured by the Comprehensive Psychopathological Rating Scale.

RESULTS

The one-year prevalence of any psychotic symptom was 7.4% (95% confidence interval [CI] 3.8-12.5); including hallucinations 6.7% (95% CI 3.4-11.8) and delusions 0.6% (95% CI 0.0-3.4). Four (2.4%) individuals fulfilled DSM-III-R criteria for schizophrenia. Individuals with psychotic symptoms or paranoid ideation did not differ regarding cognitive functioning compared with individuals without these symptoms. Individuals with hallucinations and paranoid ideation had an increased frequency of previous paranoid personality traits compared with individuals without psychotic symptoms and paranoid ideation. No individuals with psychotic symptoms had a formal thought disorder, incoherence of speech, or flat affect.

CONCLUSION

The authors found a high prevalence of psychotic symptoms, paranoid ideation, and schizophrenia in the very old. Most of the symptoms were elucidated by information from key informants, illustrating the importance of including relatives in the evaluation of elderly persons.

摘要

目的

研究95岁非痴呆老人中精神病性症状和精神分裂症的1年患病率,并探讨精神病性症状与其他精神症状、感觉障碍及认知功能之间的关系。

参与者

代表性样本为居住在瑞典哥德堡的95岁老人(N = 338)。排除患有痴呆症的个体(N = 175),本研究共纳入163名受试者。

设计

这是一项横断面人群研究,包括精神科和体格检查、认知测试以及与亲密知情者的访谈。

测量

根据《精神疾病诊断与统计手册》第三版(DSM - III)对精神分裂症、精神病性症状、偏执观念和痴呆进行诊断测量。使用简易精神状态检查表测试认知功能。通过综合精神病理学评定量表测量其他精神症状。

结果

任何精神病性症状的1年患病率为7.4%(95%置信区间[CI] 3.8 - 12.5);其中幻觉患病率为6.7%(95% CI 3.4 - 11.8),妄想患病率为0.6%(95% CI 0.0 - 3.4)。4名(2.4%)个体符合DSM - III - R精神分裂症标准。有精神病性症状或偏执观念的个体与没有这些症状的个体在认知功能方面无差异。与没有精神病性症状和偏执观念的个体相比,有幻觉和偏执观念的个体既往偏执型人格特质的频率更高。没有精神病性症状的个体存在形式思维障碍、言语不连贯或情感平淡。

结论

作者发现高龄老人中精神病性症状、偏执观念和精神分裂症的患病率较高。大多数症状通过关键知情者提供的信息得以阐明,这表明在评估老年人时纳入亲属的重要性。

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